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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC23 All Species: 26.06
Human Site: S125 Identified Species: 40.95
UniProt: Q9UJX2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJX2 NP_004652.2 597 68834 S125 Y M Y S R Y L S G E K K K D D
Chimpanzee Pan troglodytes XP_517953 597 68798 S125 Y M Y S R Y L S G E K K K D D
Rhesus Macaque Macaca mulatta XP_001112573 597 68791 S125 Y M Y S R Y L S G E K K K D D
Dog Lupus familis XP_538647 597 68772 S125 Y M Y S R Y L S G E K K K D D
Cat Felis silvestris
Mouse Mus musculus Q8BGZ4 597 68543 S125 Y M Y S R Y L S G E K K K D D
Rat Rattus norvegicus NP_001094129 597 68604 S125 Y M Y S R Y L S G E K K K D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079890 580 67402 L123 T V D S L G P L E K G Q V K N
Zebra Danio Brachydanio rerio NP_957227 579 66924 L124 T V D S L G P L E K G Q V R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610036 678 77547 D125 R R L D S T T D Q A N L H E P
Honey Bee Apis mellifera XP_396943 575 67150 K124 V V P P D P L K N E S L R L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782099 467 54518 W23 R K D F N L P W I K R D L V C
Poplar Tree Populus trichocarpa XP_002318627 576 67353 A132 R C Y A L Y L A G E K R K E E
Maize Zea mays NP_001147126 599 68030 C125 L A K T Y F D C R E Y R R A A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190398 579 67116 A134 R Y Y A L Y L A G E K R K E E
Baker's Yeast Sacchar. cerevisiae P16522 626 73096 S127 K L Y S K F L S W D K K S Q E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 98.6 N.A. 95.3 95.6 N.A. N.A. N.A. 86.7 77.8 N.A. 40.1 51.7 N.A. 47.7
Protein Similarity: 100 100 99.5 99.5 N.A. 97.4 97.6 N.A. N.A. N.A. 91.7 86.7 N.A. 55.4 68.5 N.A. 60.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 6.6 6.6 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 33.3 33.3 N.A. 6.6 26.6 N.A. 13.3
Percent
Protein Identity: 40.3 41.2 N.A. 41.7 29.3 N.A.
Protein Similarity: 57.7 57.9 N.A. 57.4 48.4 N.A.
P-Site Identity: 46.6 6.6 N.A. 46.6 40 N.A.
P-Site Similarity: 80 33.3 N.A. 80 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 0 0 0 14 0 7 0 0 0 7 7 % A
% Cys: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 7 % C
% Asp: 0 0 20 7 7 0 7 7 0 7 0 7 0 40 40 % D
% Glu: 0 0 0 0 0 0 0 0 14 67 0 0 0 20 20 % E
% Phe: 0 0 0 7 0 14 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 14 0 0 54 0 14 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 7 7 7 0 7 0 0 7 0 20 60 47 54 7 0 % K
% Leu: 7 7 7 0 27 7 67 14 0 0 0 14 7 7 7 % L
% Met: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 7 0 7 0 0 0 14 % N
% Pro: 0 0 7 7 0 7 20 0 0 0 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 14 0 7 0 % Q
% Arg: 27 7 0 0 40 0 0 0 7 0 7 20 14 7 0 % R
% Ser: 0 0 0 60 7 0 0 47 0 0 7 0 7 0 0 % S
% Thr: 14 0 0 7 0 7 7 0 0 0 0 0 0 0 0 % T
% Val: 7 20 0 0 0 0 0 0 0 0 0 0 14 7 0 % V
% Trp: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % W
% Tyr: 40 7 60 0 7 54 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _